| 01 Distribution | Rome | 2001 | 3 |
| 1-2-3 Production | — | 2016 | 2 |
| 10 West Studios | Manistee | — | 2 |
| 101 | — | — | 1 |
| 12-Gauge Production | — | — | 1 |
| 13ème Rue Universal | — | 1997 | 1 |
| 19 Entertainment | London | February 14, 1985 | 3 |
| 2 Player Productions | Portland | 2005 | 1 |
| 2003 Productions | — | — | 1 |
| 20th Century Studios | Fox Plaza, Walt Disney Studios | 1985 | 1,095 |
| 20th Century Studios Home Entertainment | Century City, Los Angeles | 1976 | 3 |
| 20th Television Animation | Los Angeles | May 19, 1999 | 1 |
| 21 Laps Entertainment | — | 2005 | 15 |
| 21Sextury | Scottsdale | 2003 | 1 |
| 21st Century Film Corporation | Los Angeles | 1971 | 6 |
| 21st Century Hero Film Investment | — | — | 1 |
| 24 images | Montreal | 1979 | 1 |
| 2:10 AM Animation | Wuhan | September 8, 2011 | — |
| 2D films | Moscow | 2010 | 1 |
| 2M TV | Casablanca | March 4, 1989 | 5 |
| 2S Films | — | — | 4 |
| 2V Media | Leningradsky Avenue, Moscow | 1992 | 1 |
| 3 Arts Entertainment | Beverly Hills | 1991 | 8 |
| 3 Mills Studios | — | — | 1 |
| 30West | Santa Monica | 2017 | 1 |
| 3B-Produktion | Berlin | June 18, 2013 | 2 |
| 3DD Productions | London Borough of Camden | — | 1 |
| 4 Mecs en Baskets | Paris | 2000 | 1 |
| 4-Play Video | — | — | 7 |
| 40 Acres & A Mule Filmworks | Brooklyn, New York City | 1983 | 37 |
| 42 km film | Bucharest | 2004 | 1 |
| 42nd Street Productions | — | — | 1 |
| 4Kids TV | — | September 14, 2002 | — |
| 4S Production | Prague | March 17, 1997 | 1 |
| 4½ Entertainment | Oslo | April 2, 2013 | 10 |
| 51 Minds Entertainment | Los Angeles | 2004 | 5 |
| 6253032 Canada Inc. | — | — | 1 |
| 6893619 Canada Inc. | — | — | 1 |
| 8565686 Canada Inc. | — | — | 1 |
| 87North Productions | Santa Monica | April 2019 | 10 |